By Philip M. Parker
In March 2001, the nationwide Institutes of healthiness issued the next caution: ''The variety of websites supplying health-related assets grows on a daily basis. Many websites offer important details, whereas others could have info that's unreliable or misleading.'' in addition, due to the quick elevate in Internet-based details, many hours should be wasted looking out, deciding on, and printing. due to the fact that basically the smallest fraction of data facing bladder melanoma is listed in se's, similar to www.google.com or others, a non-systematic method of web study could be not just time eating, but additionally incomplete. This ebook was once created for doctors, scholars, and contributors of most of the people who are looking to behavior clinical learn utilizing the main complex instruments on hand and spending the smallest amount of time doing so.
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Extra info for Bladder Cancer - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers
273-9 Sao Paulo, Timing: Fiscal Year 2004; Project Start 20-SEP-2002; Project End 30-JUN-2007 Summary: (provided by applicant) The main goal of this project is to investigate the whether inactivation of E-cadherin, Beta and gamma-catenins can be used as biomarkers for bladder cancer initiation / progression or metastasis. Also investigate the molecular mechanisms of inactivation of E-cadherin, Beta and gamma-catenins in bladder cancer through mutation / CpG methylation pathways. We will also investigate the functional role of the E-cadherin, Beta, and gamma catenins genes in bladder cancer.
S. population to arsenic concentrations in the 5-100 mg/L range where no information currently exists. S. Environmental Protection Agency to reduce the maximum contaminant level for arsenic in our drinking water have been bedeviled by contradictory and unvalidated predictions of the risks of chronic exposure to low levels (< 100 mg/L) of arsenic in water. ; Professor; Harvard University (Sch of Public Hlth) Public Health Campus Boston, Ma 02115 Timing: Fiscal Year 2004 Summary: Arsenic poses unique problems for environmental health scientists in that it is recognized as a human carcinogenic but is not carcinogenic in animal models.
It is proposed to investigate a therapeutic strategy involving intravesical (bladder) delivery of small interfering RNAs (siRNAs) to downregulate complement inhibitory proteins on bladder tumor cells, together with intravenous administration of a complement activating mAb directed against a bladder cancer-associated antigen. Optimum siRNA sequences for downregulation of complement inhibitory proteins on a mouse bladder cancer cell line will be determined in vitro. Selected siRNA sequences will be used to determine optimum strategy for siRNA/gene delivery to tumor cells in an orthotopic syngeneic mouse model of bladder cancer.
Bladder Cancer - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers by Philip M. Parker