Brain Oncology Biology, diagnosis and therapy: An by C. C. Tijssen (auth.), M. Chatel, F. Darcel, J. Pecker PDF

By C. C. Tijssen (auth.), M. Chatel, F. Darcel, J. Pecker (eds.)

ISBN-10: 9400933479

ISBN-13: 9789400933477

ISBN-10: 9401080038

ISBN-13: 9789401080033

The overseas assembly on mind Oncology in Rennes was once organised in honor of Jean Pecker, to pay tribute to his contribution to the improvement of neurological sciences and to take inventory of the present kingdom of data on mind tumors, a site during which the function of neurosurgery has been and should stay primordial. in the course of the two-day convention, the most important issues of mind oncology reviews, either basic and medical, have been tested: oncogenesis, tumoral markers and immunology, metabolic and analysis imaging, prognostic elements and healing concepts. the big quantity and top of the range of participations ended in a certainly artificial view of present advances in examine, of which this booklet offers the necessities. we've tried either to maintain the richness of medical exchanges which happened and to post a superb many oral and poster communications. The publication respects the association of convention periods, and therefore displays the significance accorded to glial tumor reviews. this can appear disproportionate given their frequency of prevalence in percentage to overall numbers of intracranial tumor techniques, yet their gravity and quasi-total resistance to present healing equipment are plentiful justification. in addition, this can be the area during which hopes of growth are starting to look, and it truly is turning into attainable to envisage therapy in accordance with lately proven primary knowledge.

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Extra info for Brain Oncology Biology, diagnosis and therapy: An international meeting on brain oncology, Rennes, France, September 4–5, 1986, held under the auspices of the Ministry of National Education, the University of Rennes and the Regional Hospital Rennes

Example text

Darcel and J. ). Brain Oncology. ISBN-B: 978-94-010-8003-3 Dordrecht. © 1987. Martinus Nijhoff Publishers. 16 RENNES, 4-5 SEPTEMBRE 1986 - IMBO/JIOC Hybridization probes Viral and oncogenic DNA probes were used in this study. Herpes Simplex Virus type 1 and 2 (HSV-I and -2) DNAs were purified at the Montreal Cancer Institute (19), Simian Virus 40 (SV 40) and Adenovirus type 2 (Ad 2) DNAs were a gift from Dr. E. Frost (Montreal Cancer Institute). 10 viral Oncogene probes (Ha- and Ki-ras, mos, myc, myb, N-myc, abI, erb-A, fes, sis) were purchased from ON COR, USA.

8 (most frequent), n. 9, n. 14 and n. 15 (5). The loss of either the X or Y has been reported in a significant number of meningiomas accompanied by other chromosomal changes (5). In the present study we report the results of the cytogenetic findings in 25 out of 40 utilized human meningiomas. According to the literature, several tumors showed chromosome n. 22 abnormalities (monosomy and rearrangement), chromosome n. 8 monosomy and trisomy, chromosomes rearrangement n. 1, n. 7 and n. 9. In a small number of tumors the chromosomes X or Y were lost.

Expression of cellular oncogenes in human malignancies. Science, 224, 256-262 (1984). 17. ): Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. , 98,503-517 (1975). 18. ): DNA related to the transforming gene(s) of avian sarcoma virus is present in normal avian DNA. Nature, 260, 170-173 (1976). 19. ): Localization of the coding region for a 35 000 Dalton polypeptide on the genome of Herpes Simplex virus type 2. J. Gen. , 64, 2079-2085 (1983). H. BIGNER (0).

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Brain Oncology Biology, diagnosis and therapy: An international meeting on brain oncology, Rennes, France, September 4–5, 1986, held under the auspices of the Ministry of National Education, the University of Rennes and the Regional Hospital Rennes by C. C. Tijssen (auth.), M. Chatel, F. Darcel, J. Pecker (eds.)


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