As the inspiration and discoveries of melanoma stem cells are fairly new, scientists and researchers desire an creation to this dynamic sector. melanoma Stem Cells provides a consolidated account of the learn performed to this point and up to date progresses within the experiences of melanoma stem cells. this kind of presentation allows a greater realizing of and attracts realization to stem telephone and melanoma biology - fields that improve, circulation, and evolve into one another always. It presents an informative learn in designing techniques to use stem cellphone ideas to melanoma biology whereas providing an summary of the demanding situations in constructing blend stem and melanoma biology goals for therapeutics. This ebook serves as a primer for brand spanking new researchers within the box of melanoma biology.
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Extra resources for Cancer Stem Cells: Identification and Targets
Costa FF, Le Blanc AK, Brodin BB. Cancer/testis antigens, stem cells and cancer. Stem Cells. 2007; 25:707–711. 5. McCulloch EA, Till JE. Perspectives on the properties of stem cells. Nat Med. 2005; 11:1026–1028. 6. Wicha MS, Liu S, Dontu G. Cancer stem cells: an old idea—a paradigm shift. Cancer Res. 2006; 66:1883–1890. 7. Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001; 414:105–111. 8. Ralston A, Rossant J. Genetic regulation of stem cell origins in the mouse embryo.
1906; 1:140–141. 4. Costa FF, Le Blanc AK, Brodin BB. Cancer/testis antigens, stem cells and cancer. Stem Cells. 2007; 25:707–711. 5. McCulloch EA, Till JE. Perspectives on the properties of stem cells. Nat Med. 2005; 11:1026–1028. 6. Wicha MS, Liu S, Dontu G. Cancer stem cells: an old idea—a paradigm shift. Cancer Res. 2006; 66:1883–1890. 7. Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001; 414:105–111. 8. Ralston A, Rossant J. Genetic regulation of stem cell origins in the mouse embryo.
When the cancer develops in the lymphocytes (lymphoid lineage), it is called lymphocytic leukemia, while cancer of the granulocytes or monocytes (myeloid lineage) is described as myelogenous leukemia. The rate of disease progression is an additional feature used for classification. In chronic leukemias, the immature hematopoietic progenitors (colloquially referred to as blasts) accumulate slowly and continue to form functional hematopoietic cells; because of this, disease progression is slow. On the other hand, in acute leukemias, the progenitors proliferate rapidly, resulting in blast accumulation, decreased turnover of mature hematopoietic cells, and rapid disease progression.
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